Setting aside for a moment the
definition of “Diabetic” and “Pre-Diabetic” (It’s a can of worms.), each person
who has been diagnosed with a degree of Insulin Resistance (IR) has to decide,
with their doctor in most cases, the
method and degree of “countermeasures” that they think is prudent to
avert “the dreaded complications.”
The complications are an increased
likelihood of the familiar microvascular complications: retinopathy, (leading to blindness), peripheral
neuropathy (ending in amputations) and nephropathy (ultimately, end stage
kidney disease with dialysis), not to mention Erectile Dysfunction (ED). They
also include macrovascular complications like heart attack and stroke…and a significantly greater chance of
dementia, including Alzheimer’s Disease (AD). And overall, a reduction in life expectancy of up to 10 years.
The American Diabetes Association describes
Type 2 Diabetes as a “progressive” disease. To delay (not
avert) the progression, most physicians employ the “usual care”
Standard of Practice and advise diet (to lose weight) and exercise (175 minutes
a week). Weight gain is associated
with Prediabetes and Type 2 Diabetes and
falsely viewed by most doctors as a “cause” of Type 2. In truth, Type 2
diabetes is caused by Insulin Resistance , and Insulin Resistance causes weight gain. IR comes
first. Weight loss, unless the diet is Low Carb and eating Low Carb becomes a “lifestyle change,” will not
be permanent. And, knowing that “diet and exercise” will fail, within 3 months
of a Type 2 (or Pre-Diabetes) diagnosis, most doctors will prescribe drugs, starting
with Metformin.
Depending on the patient’s age and
other health conditions, the doctor will have in mind a marker of glucose
control. Today, the A1c blood test has become the new marker. It measures the
percentage of glucose on the surface of your red blood cells. These cells have
an average life of 2-3 months, so it’s considered the average level of glucose
in your blood, 24/7, over that period. It’s a nifty surrogate, and inexpensive.
Here’s where it starts to get
sticky. The Quest Laboratory test reports say, “According to ADA guidelines, a
hemoglobin A1c <7.0% represents optimal [emphasis added by me]
control in non-pregnant diabetic patients.” It goes on to say, “Different
metrics may apply to specific patient populations.” This is meant to imply that
as you get older (say, 75 or 80 years old), the ADA counsels your doctor to consider
an A1c of <8% to be “optimal”!
Important note: the ADA considers a <7.0% A1c “optimal”
for a patient already diagnosed as a full-blown Type 2. For the not-as
yet-diagnosed Type 2, the Quest report gives the ADA guidelines for screening
for diabetes:
<5.7% Consistent
with the absence of diabetes
5.7-6.4% Consistent
with increased risk of diabetes (Pre-Diabetes)
≥6.5% Consistent
with diabetes
The 6.5% level is the level adopted by the medical
establishment’s metabolic specialists, the American College of
Endocrinologists. Note how 6.5% is well below the level that the ADA
considers “optimal” (<7.0 or <8.0%). What does that tell you about how
confident your doctor and the medical/pharmaceutical establishment are of
their
(and your) ability to effectively control your blood sugar to
treat your disease? That’s why, acknowledging the likelihood of failure
both in achieving permanent weight
loss and
blood sugar control, Type 2 is considered “progressive.” You will, over time, if you
follow their dietary advice, need to take progressively more medication.
So, is an A1c of <7.0% (or <8.0% if you are elderly) the
target that you and your doctor have “negotiated”?
Or, is <6.5% your target, to avoid being officially
diagnosed a type 2 (by current “official” medical standards)?
Or, is <5.7% your target, so you can comfort yourself with
the phrase, “consistent with the absence of diabetes”?
Or, is an A1c in the “low 5s” your target? It has been for me
for half of the 30 years since I was diagnosed a Type 2 Diabetic . My doctor is
much more relaxed, though. He, like most, considers the ADA’s <7.0% “well
controlled.”
Or, is an A1c under 5.0% your target? I know many long-term
Type 2s who manage their disease this way, to
their advantage, as you’ll see. Most of them do this with a combination of
a strict Low Carb diet and insulin injections.
So, just how diabetic do you want to be? Next week, I will explore, by
multivariate-adjusted hazard ratio (HR), the
cardiovascular (CVD) risk of the choice you will make.
It’s not
complicated, as you’ll see.
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