In February 2016, as I prepared to leave Bogotá, Colombia, after
3 weeks of studying Spanish, a few thoughts related to type 2 diabetes came to
mind. Bogotá is a burgeoning city, growing leaps and bounds, transitioning from
“a feudal society” (to quote the husband of my teacher) to a modern,
invigorating, stimulating place. I loved it, and it’s exciting to see the
changes coming about, but also shocking to see the stark contrasts. For
grounding and perspective, the husband reminded me that women only gained the
right to vote in 1957.
For me personally the most surprising discovery was that the
brand new, modern apartment I rented, that had multiple USB connections in
every room, has no central heat! Further, there is no hot water in the kitchen
– only in the bathroom, supplied by an electric in-line hot water heater for
the sink and shower.
At first, I thought that this was a factor of the
neighborhood (services are taxed by “estrado”). This method of taxing services
by socio-economic status is designed to give preference (“subsidies”) to the
less advantaged. Unfortunately, it also results in stagnation and immobility by
stigmatizing the poorer neighborhoods.
Later, I discovered that the modern, well-designed apartment
of my teacher and her husband (both PhD’s teaching at the National University) also
has no central heating and no hot water
in the kitchen. ¡Qué sorpresa! They live in an upscale neighborhood in the
northern reaches of the city. The “no heat” explanation relates in part to the
climate. Bogotá has a moderate climate year-round. It is located close to the
equator but at a very high elevation (8,675 feet or 2,644 meters), so
temperatures are constant all year round. It never snows.
So this partially explains the central heating issue, but not
the lack of kitchen hot water. “How do you wash dishes,” I asked the husband as
he did them. “I scrub them well,” he said.
Does that give you perspective?
Type 2 diabetes is similarly just emerging from the dark
ages. One hundred and fifty years ago type 2 diabetes was understood as a
dietary disease (see Retrospective #1 re: French physiologist Claude Bernard
and English undertaker William
Banting). It was known as a disease of excessive consumption of carbohydrates
and was treated by reducing carbohydrates in the diet. Then, in 1921, Frederick Banting (bizarrely, a
distant relation!) discovered how to make insulin in the lab, and since then
type 2 diabetes has been treated like type 1 diabetes, a disease of too little insulin.
When our insulin receptor cells resist the uptake of glucose,
i.e. they express Insulin Resistance (IR), the pancreas produces more insulin
until it eventually wears out. Doctors hasten this catastrophic failure of the
pancreas by adding pharmaceuticals, like sulfonylureas (Micronase, glyburide,
glipizide, et al.) to push the pancreas to exhaustion. Then, the doctors
add injected insulin to the patient’s regimen. This medieval practice, not unlike “bleeding
the patient,” is still the Standard of Care of the medical establishment and their
government overseers in the United States.
Until recently. We are finally beginning to see a
Renaissance. Increasingly type 2 diabetes is being understood again as a
disease of Insulin Resistance, resulting in too
much insulin. The goal in treating type 2 diabetes should be not only
to lower the glucose level in the blood (by
diet instead of drugs), but also to lower
the insulin level in the blood.
This will occur, and will only
occur, when the glucose level lowers, because that is how the body
“knows” that it needs to begin to burn fat for fuel (triglycerides, in the form
of body fat stored around the “trunk,”) to maintain energy balance and a fully
active metabolism. The body, including heart and brain, loves these
fatty acids and the ketone bodies that are produced as a side effect of
lipolysis (the break-down of triglycerides to fatty acids).
And, if you’re interested, THIS IS ALSO BEST WAY TO
LOSE WEIGHT, EASILY AND WITHOUT EVER FEELING HUNGRY.
Bogotá is rapidly transforming itself. ¡Ojalá
que el mundo de los diabéticos se haga lo mismo! Y pronto.
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